A group of scientists have been working in a secret laboratory, attempting to create the strongest Pokemon yet in existence. Unaware of their creation’s power, the scientists and their laboratory are destroyed by the awakening Mewtwo. Angered at his creators for making him the Pokemon equivalent of Frankenstein’s monster, Mewtwo swears revenge on the world.

Mewtwo hatches a plan to hijack the globe with a specially created race of Super-Pokemon. What follows is the ultimate Pokemon match of all time, ending with a face-off between Mewtwo and the rare and powerful Mew.