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Wisecracking mercenary Deadpool meets Russell, an angry teenage mutant who lives at an orphanage. When Russell becomes the target of Cable -- a genetically enhanced soldier from the future -- Deadpool realizes that he'll need some help saving the boy from such a superior enemy. He soon joins forces with Bedlam, Shatterstar, Domino and other powerful mutants to protect young Russell from Cable and his advanced weaponry.
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